FEATURES

FAMILY

DESCRIPTION

Also known as SRSF6_HUMAN, SRSF6, SFRS6, SRP55. Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing. Binds SREK1/SFRS12. Interacts with DYRK1A.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SRSF6

Serine/arginine-rich splicing factor 6

SRSF6

Molecular Synopsis