FEATURES

FAMILY

polyadenylate-binding protein type-1 family

DESCRIPTION

Also known as PABP4_HUMAN, PABPC4, APP1, PABP4. Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Interacts with NFX1. Interacts with ZFC3H1 in a RNase-sensitive manner (PubMed:27871484).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PABPC4

Polyadenylate-binding protein 4

PABPC4

Molecular Synopsis