FEATURES

FAMILY

DESCRIPTION

Also known as ITAD_HUMAN, ITGAD. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood. Heterodimer of an alpha and a beta subunit. Alpha-D associates with beta-2.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ITGAD

Integrin alpha-D

ITGAD

Molecular Synopsis