FEATURES

DESCRIPTION

Also known as OLIG2_HUMAN, OLIG2, BHLHB1, BHLHE19, PRKCBP2, RACK17. Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. Interacts with NKX2-2. Interacts with ZNF488.

Also known as OLIG2_HUMAN, OLIG2, BHLHB1, BHLHE19, PRKCBP2, RACK17. Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic moto ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

OLIG2

Oligodendrocyte transcription factor 2

OLIG2

Molecular Synopsis