FEATURES

FAMILY

DESCRIPTION

Also known as SPTN1_HUMAN, SPTAN1, NEAS, SPTA2. Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Like erythrocyte spectrin, the spectrin-like proteins are capable of forming dimers which can further associate to tetramers. Interacts (via C-terminal spectrin repeats) with TRPC4. Interacts with CALM and EMD. Interacts with isoform 1 of ACP1. Identified in a complex with ACTN4, CASK, IQGAP1, MAGI2, NPHS1 and SPTBN1. Interacts with SHANK3 (via ANK repeats). Interacts with CLN3; this interaction regulates the fodrin localization at the plasma membrane (Probable).

Also known as SPTN1_HUMAN, SPTAN1, NEAS, SPTA2. Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-depe ...

EXTERNAL LINKS

SPTAN1

Spectrin alpha chain, non-erythrocytic 1

SPTAN1

Molecular Synopsis