FEATURES

FAMILY

DESCRIPTION

Also known as CNCG_HUMAN, PDE6H. Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones. Tetramer composed of two catalytic chains (alpha and beta), and two inhibitory chains (gamma).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PDE6H

Retinal cone rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase subunit gamma

PDE6H

Molecular Synopsis