FEATURES

FAMILY

fibroblast growth factor-binding protein family

DESCRIPTION

Also known as FGFP1_HUMAN, FGFBP1, FGFBP, HBP17. Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGF1, FGF2, FGF7, FGF10, FGF22 and HSPG2.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FGFBP1

Fibroblast growth factor-binding protein 1

FGFBP1

Molecular Synopsis