FEATURES

FAMILY

DESCRIPTION

Also known as NC2A_HUMAN, DRAP1. The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Heterodimer with DR1. Binds BTAF1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DRAP1

Dr1-associated corepressor

DRAP1

Molecular Synopsis