FEATURES

FAMILY

DESCRIPTION

Also known as OXA1L_HUMAN, OXA1L. Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria. Monomer; predominantly monomeric at low salt concentrations. Homooligomer; predominantly homooligomeric at high salt concentrations. Homodimer. Homotetramer. Interacts with MRPL13, MRPL20, MRPL28, MRPL48, MRPL49 and MRPL51. Associates preferentially as a dimer with the large ribosomal subunit 39S of the mitochondrial ribosome.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

OXA1L

Mitochondrial inner membrane protein OXA1L

OXA1L

Molecular Synopsis