FEATURES

FAMILY

DESCRIPTION

Also known as ELF2_HUMAN, ELF2, NERF. Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter., Isoform 2 may function in repression of RUNX1-mediated transactivation. Interacts with the LIM domains of LMO2 (By similarity). Interacts via its N-terminal region with RUNX1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ELF2

ETS-related transcription factor Elf-2

ELF2

Molecular Synopsis