FEATURES

FAMILY

inositol 1,4,5-trisphosphate 5-phosphatase type II family

DESCRIPTION

Also known as PI5PA_HUMAN, INPP5J, PIB5PA, PIPP. Inositol 5-phosphatase, which converts inositol 1, 4, 5-trisphosphate to inositol 1, 4-bisphosphate. Also converts phosphatidylinositol 4, 5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1, 3, 4, 5-tetrakisphosphate to inositol 1, 3, 4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

INPP5J

Phosphatidylinositol 4, 5-bisphosphate 5-phosphatase A

INPP5J

Molecular Synopsis