FEATURES

FAMILY

DESCRIPTION

Also known as TBCC_HUMAN, TBCC. Tubulin-folding protein; involved in the final step of the tubulin folding pathway. Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TBCC

Tubulin-specific chaperone C

TBCC

Molecular Synopsis