FEATURES

FAMILY

DESCRIPTION

Also known as TKFC_HUMAN, TKFC, DAK. Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response (PubMed:17600090). Homodimer (By similarity). Interacts with IFIH1 (via the CARD domains), the interaction is inhibited by viral infection (PubMed:17600090).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TKFC

Triokinase/FMN cyclase

TKFC

Molecular Synopsis