FEATURES

FAMILY

DESCRIPTION

Also known as CDNF_HUMAN, CDNF, ARMETL1. Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CDNF

Cerebral dopamine neurotrophic factor

CDNF

Molecular Synopsis