FEATURES

FAMILY

DESCRIPTION

Also known as ZN326_HUMAN, ZNF326, ZIRD. Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro. Component of the DBIRD complex. Interacts with CCAR2; the interaction is direct.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ZNF326

DBIRD complex subunit ZNF326

ZNF326

Molecular Synopsis