FEATURES

FAMILY

DESCRIPTION

Also known as FILA2_HUMAN, FLG2, IFPS. Essential for normal cell-cell adhesion in the cornified cell layers (PubMed:29758285). Important for proper integrity and mechanical strength of the stratum corneum of the epidermis (PubMed:29505760).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FLG2

Filaggrin-2

FLG2

Molecular Synopsis