FEATURES

FAMILY

DESCRIPTION

Also known as SPDYC_HUMAN, SPDYC. Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase. Interacts with CDK1 and CDK2. Interacts with AURKB.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SPDYC

Speedy protein C

SPDYC

Molecular Synopsis