FEATURES

FAMILY

DESCRIPTION

Also known as EOGT_HUMAN, EOGT, AER61, C3orf64, EOGT1. Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EOGT

EGF domain-specific O-linked N-acetylglucosamine transferase

EOGT

Molecular Synopsis