FEATURES

FAMILY

DESCRIPTION

Also known as BRM1L_HUMAN, BRMS1L. Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity. When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth. Component of the Sin3/HDAC1 corepressor complex at least composed of BRMS1, BRMS1L and ING2/ING1L. Interacts with HDAC and SIN3A.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

BRMS1L

Breast cancer metastasis-suppressor 1-like protein

BRMS1L

Molecular Synopsis