FEATURES

FAMILY

DESCRIPTION

Also known as CELF3_HUMAN, CELF3, BRUNOL1, CAGH4, ERDA4, TNRC4. RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.

Also known as CELF3_HUMAN, CELF3, BRUNOL1, CAGH4, ERDA4, TNRC4. RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mR ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CELF3

CUGBP Elav-like family member 3

CELF3

Molecular Synopsis