FEATURES

DESCRIPTION

Also known as FYB2_HUMAN, FYB2, ARAP, C1orf168. Adapter protein that plays a role in T-cell receptor (TCR)-mediated activation of signaling pathways. Required for T-cell activation and integrin-mediated T-cell adhesion in response to TCR stimulation (PubMed:27335501). Interacts with SKAP1, LCK and FYN. The phosphorylated form interacts with LCP2.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FYB2

FYN-binding protein 2

FYB2

Molecular Synopsis