FEATURES

FAMILY

DESCRIPTION

Also known as KFA_HUMAN, AFMID. Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

AFMID

Kynurenine formamidase

AFMID

Molecular Synopsis