FEATURES

FAMILY

DESCRIPTION

Also known as DS13A_HUMAN, DUSP13A, BEDP, DUSP13, MDSP. Probable protein tyrosine phosphatase. Has phosphatase activity with synthetic substrates (PubMed:15252030, PubMed:29106959). Has a phosphatase activity-independent regulatory role in MAP3K5/ASK1-mediated apoptosis, preventing MAP3K5/ASK1 inhibition by AKT1. Shows no phosphatase activity on MAPK1/ERK2, MAPK8/JNK, MAPK14/p38 and MAP3K5/ASK1. Monomer (PubMed:29106959). Interacts with MAP3K5/ASK1; may compete with AKT1 preventing MAP3K5/ASK1 phosphorylation by AKT1.

Also known as DS13A_HUMAN, DUSP13A, BEDP, DUSP13, MDSP. Probable protein tyrosine phosphatase. Has phosphatase activity with synthetic substrates (PubMed:15252030, PubMed:29106959). Has a phospha ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DUSP13A

Dual specificity protein phosphatase 13A

DUSP13A

Molecular Synopsis