FEATURES

FAMILY

DESCRIPTION

Also known as SIR5_DANRE, sirt5. NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.

EXTERNAL LINKS

uniprot
enzyme classification

sirt5

NAD-dependent protein deacylase sirtuin-5, mitochondrial

sirt5

Molecular Synopsis