FEATURES

DESCRIPTION

Also known as FCRL6_HUMAN, FCRL6, FCRH6. Acts as a MHC class II receptor (PubMed:20519654). When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells (PubMed:17213291, PubMed:18991291). Does not act as an Fc receptor (PubMed:18991291). Interacts (tyrosine phosphorylated) with PTPN11 (PubMed:17213291, PubMed:20933011). Interacts (tyrosine phosphorylated) with PTPN6, INPP5D, INPPL1 and GRB2 (PubMed:20933011). Interacts with class II MHC HLA-DR when the alpha chain is associated with a beta-1, beta-4 or a beta-5 but not a beta-3 chain (PubMed:20519654).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FCRL6

Fc receptor-like protein 6

FCRL6

Molecular Synopsis