FEATURES

FAMILY

DESCRIPTION

Also known as DEN5A_HUMAN, DENND5A, KIAA1091, RAB6IP1. Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth (By similarity). Interacts with RAB6A bound to GTP.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DENND5A

DENN domain-containing protein 5A

DENND5A

Molecular Synopsis