FEATURES

FAMILY

DESCRIPTION

Also known as SCYL2_HUMAN, SCYL2, CVAK104, KIAA1360. Component of the AP2-containing clathrin coat that may regulate clathrin-dependent trafficking at plasma membrane, TGN and endosomal system (Probable). A possible serine/threonine-protein kinase toward the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine has not been confirmed (PubMed:15809293, PubMed:16914521). By regulating the expression of excitatory receptors at synapses, plays an essential role in neuronal function and signaling and in brain development (By similarity). Interacts with clathrin and AP2B1; the interaction mediates the association with the AP-2 complex.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SCYL2

SCY1-like protein 2

SCYL2

Molecular Synopsis