FEATURES

FAMILY

DESCRIPTION

Also known as NHS_HUMAN, NHS. May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development. Interacts with the tight junction protein TJP1/ZO-1. Associates with actin-rich structures. Interacts with BRK1 and with all three members of the WAVE protein family, WASF1, WASF2 and WASF3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NHS

Actin remodeling regulator NHS

NHS

Molecular Synopsis