FEATURES

DESCRIPTION

Also known as ANR11_HUMAN, ANKRD11, ANCO1. Chromatin regulator which modulates histone acetylation and gene expression in neural precursor cells (By similarity). May recruit histone deacetylases (HDACs) to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation (PubMed:15184363). Has a role in proliferation and development of cortical neural precursors (PubMed:25556659). May also regulate bone homeostasis (By similarity). Interacts with the PAS region of the p160 coactivators.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ANKRD11

Ankyrin repeat domain-containing protein 11

ANKRD11

Molecular Synopsis