FEATURES

DESCRIPTION

Also known as OLFM4_HUMAN, OLFM4, GW112. May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. Homomultimer; disulfide-linked. Interacts with NDUFA13. Interacts with cell surface lectins (locutions ricinus communis agglutinin I, concanavalin-A and wheat germ agglutinin) and cadherin.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

OLFM4

Olfactomedin-4

OLFM4

Molecular Synopsis