FEATURES

DESCRIPTION

Also known as THSD4_HUMAN, THSD4. Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN. Interacts with FBN1. May interact with TGFB1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

THSD4

Thrombospondin type-1 domain-containing protein 4

THSD4

Molecular Synopsis