FEATURES

DESCRIPTION

Also known as RBPS2_HUMAN, RBPMS2. RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system (PubMed:25064856). Binds NOG mRNA, the major inhibitor of the bone morphogenetic protein (BMP) pathway. Mediates an increase of NOG mRNA levels, thereby contributing to the negative regulation of BMP signaling pathway and promoting reversible dedifferentiation and proliferation of smooth muscle cells (By similarity). Homodimer (PubMed:25064856). Interacts with EEF2 (PubMed:25064856).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RBPMS2

RNA-binding protein with multiple splicing 2

RBPMS2

Molecular Synopsis