FEATURES

DESCRIPTION

Also known as TPGS1_HUMAN, TPGS1, C19orf20. Subunit of the tubulin polyglutamylase complex (TPGC). The complex mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility (Probable). May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). Part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1 (Probable). Interacts with PCM1, CSTPP1 and LRRC49 (PubMed:34782749).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TPGS1

Tubulin polyglutamylase complex subunit 1

TPGS1

Molecular Synopsis