FEATURES

DESCRIPTION

Also known as STOX1_HUMAN, STOX1, C10orf24. Involved in regulating the levels of reactive oxidative species and reactive nitrogen species and in mitochondrial homeostasis in the placenta (PubMed:24738702). Required for regulation of inner ear epithelial cell proliferation via the AKT signaling pathway (By similarity)., Involved in cell cycle regulation by binding to the CCNB1 promoter, up-regulating its expression and promoting mitotic entry (PubMed:22253775). Induces phosphorylation of MAPT/tau (PubMed:22995177).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

STOX1

Storkhead-box protein 1

STOX1

Molecular Synopsis