FEATURES

DESCRIPTION

Also known as SYDE1_HUMAN, SYDE1. GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1 (PubMed:27917469).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SYDE1

Rho GTPase-activating protein SYDE1

SYDE1

Molecular Synopsis