FEATURES

FAMILY

DESCRIPTION

Also known as BBS12_HUMAN, BBS12, C4orf24. Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). Involved in adipogenic differentiation (PubMed:19190184). Component of the chaperonin-containing T-complex (TRiC), a heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter (PubMed:20080638). Interacts with MKKS (PubMed:26900326).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

BBS12

Bardet-Biedl syndrome 12 protein

BBS12

Molecular Synopsis