FEATURES

DESCRIPTION

Also known as KCP_HUMAN, KCP, CRIM2, KCP1. Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways (By similarity). Interacts with BMP7 and, by doing so, enhances binding to the type I receptors that contains cytoplasmic serine/threonine protein kinase domains. Also able to interact with activin-A and TGFB1 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KCP

Kielin/chordin-like protein

KCP

Molecular Synopsis