FEATURES

FAMILY

DESCRIPTION

Also known as RAPH1_HUMAN, RAPH1, ALS2CR18, ALS2CR9, KIAA1681, LPD, PREL2, RMO1. Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion. Interacts with EVL and VASP and targets them to the leading edge (PubMed:15469845). Interacts (via Ras associating and PH domains) with RAC1 (PubMed:18499456).

Also known as RAPH1_HUMAN, RAPH1, ALS2CR18, ALS2CR9, KIAA1681, LPD, PREL2, RMO1. Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regul ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RAPH1

Ras-associated and pleckstrin homology domains-containing protein 1

RAPH1

Molecular Synopsis