FEATURES

FAMILY

chondroitin N-acetylgalactosaminyltransferase family

DESCRIPTION

Also known as CHSS3_HUMAN, CHSY3, CHSY2, CSS3. Has both beta-1, 3-glucuronic acid and beta-1, 4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CHSY3

Chondroitin sulfate synthase 3

CHSY3

Molecular Synopsis