FEATURES

FAMILY

DESCRIPTION

Also known as S35D2_HUMAN, SLC35D2, HFRC, UGTREL8. Nucleotide sugar antiporter transporting UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-glucose (UDP-Glc) from the cytosol into the lumen of the Golgi in exchange of UMP. By supplying UDP-N-acetylglucosamine, a donor substrate to heparan sulfate synthases, probably takes part in the synthesis of these glycoconjugates.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SLC35D2

Nucleotide sugar transporter SLC35D2

SLC35D2

Molecular Synopsis