FEATURES

FAMILY

DESCRIPTION

Also known as SSH2_HUMAN, SSH2, KIAA1725, SSH2L. Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. Interacts with filamentous actin.

Also known as SSH2_HUMAN, SSH2, KIAA1725, SSH2L. Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SSH2

Protein phosphatase Slingshot homolog 2

SSH2

Molecular Synopsis