FEATURES

FAMILY

DESCRIPTION

Also known as NDUF7_HUMAN, NDUFAF7, C2orf56. Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (PubMed:20406883, PubMed:24089531, PubMed:24838397). Acts by mediating symmetric dimethylation of 'Arg-118' of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex (PubMed:24089531). Interacts with NDUFS2 (PubMed:20406883, PubMed:24089531).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NDUFAF7

Protein arginine methyltransferase NDUFAF7, mitochondrial

NDUFAF7

Molecular Synopsis