FEATURES

FAMILY

DESCRIPTION

Also known as DPH6_HUMAN, DPH6, ATPBD4. Amidase that may catalyze the last step of diphthamide biosynthesis using ammonium and ATP (PubMed:23169644). Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor (EEF2) to diphthamide (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DPH6

Diphthine--ammonia ligase

DPH6

Molecular Synopsis