FEATURES

DESCRIPTION

Also known as KANL1_HUMAN, KANSL1, CENP-36, KIAA1267, MSL1V1, NSL1. As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1. Interacts with KAT8; the interaction is direct.

Also known as KANL1_HUMAN, KANSL1, CENP-36, KIAA1267, MSL1V1, NSL1. As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may ...

EXTERNAL LINKS

KANSL1

KAT8 regulatory NSL complex subunit 1

KANSL1

Molecular Synopsis