FEATURES

FAMILY

DESCRIPTION

Also known as MON2_HUMAN, MON2, KIAA1040, SF21. Plays a role in regulating membrane trafficking of cargo proteins. Together with ATP9A and DOP1B, regulates SNX3 retromer-mediated endosomal sorting of WLS away from lysosomal degradation. Homooligomer (PubMed:30213940). Heterotrimer with ATP9A and DOP1B; this interaction is retromer-independent (PubMed:30213940). Interacts with SNX3 (PubMed:30213940).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MON2

Protein MON2 homolog

MON2

Molecular Synopsis