FEATURES

FAMILY

DESCRIPTION

Also known as K1C25_HUMAN, KRT25, KRT25A. Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization (PubMed:26902920). Heterodimer of a type I and a type II keratin (PubMed:26902920). Heterodimer with type II keratin KRT5 leading to the formation of keratin intermediate filament (KIF) network (PubMed:28899683). Interacts with KRT6A to form filaments (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KRT25

Keratin, type I cytoskeletal 25

KRT25

Molecular Synopsis