FEATURES

FAMILY

DESCRIPTION

Also known as TRI46_HUMAN, TRIM46, TRIFIC. Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity and proper neuronal migration. Interacts with TUBB3 and TUBA4A.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TRIM46

Tripartite motif-containing protein 46

TRIM46

Molecular Synopsis