FEATURES

FAMILY

DESCRIPTION

Also known as PIGW_HUMAN, PIGW. Required for the transport of GPI-anchored proteins to the plasma membrane (PubMed:24367057). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PIGW

Phosphatidylinositol-glycan biosynthesis class W protein

PIGW

Molecular Synopsis