FEATURES

FAMILY

DESCRIPTION

Also known as GALT5_HUMAN, GALNT5. Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward EA2 peptide substrate, but has a weak activity toward Muc2 or Muc1b substrates (By similarity). Interacts with EXT2. Does not interact with EXT1, EXTL1 or EXTL3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GALNT5

Polypeptide N-acetylgalactosaminyltransferase 5

GALNT5

Molecular Synopsis