FEATURES

DESCRIPTION

Also known as MARH3_HUMAN, MARCHF3, MARCH3, RNF173. E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. Interacts with MARCHF2 and STX6.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MARCHF3

E3 ubiquitin-protein ligase MARCHF3

MARCHF3

Molecular Synopsis